THERAPEUTIC INSULIN PREPARATION AND A PROCESS FOR THE PRODUCTION OF A STABLE INSULIN PREPARATION WITH PROTRACTED EFFECT

THERAPEUTIC INSULIN PREPARATION AND A PROCESS FOR THE PRODUCTION OF A STABLE INSULIN PREPARATION WITH PROTRACTED EFFECT

Novel stable insulin preparation with protracted action and low antigenicity is obtained by reacting insulin in stabilized monomer or loosely aggregated form with an organic compound having basic groups, preferably a basic polypeptide or a cleavage product of a basic polypeptide, such as protamine.

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Bibliographische Detailangaben
Hauptverfasser: ANDRESEN, FINN H, HANSEN, BRUNO A
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Novel stable insulin preparation with protracted action and low antigenicity is obtained by reacting insulin in stabilized monomer or loosely aggregated form with an organic compound having basic groups, preferably a basic polypeptide or a cleavage product of a basic polypeptide, such as protamine.