STEROIDS

This specification relates to the production of 9.alpha.-halo-11.beta.-hydroxy-corticosteroids, to intermediates used in the production of such steroids, and to the production of such intermediates themselves. The specification is particularly concerned with the production of such steroids having an...

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Hauptverfasser: TORABI, HOUSHANG, MORROW, DUANE F, LEVINSKY, HENRY L
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creator TORABI, HOUSHANG
MORROW, DUANE F
LEVINSKY, HENRY L
description This specification relates to the production of 9.alpha.-halo-11.beta.-hydroxy-corticosteroids, to intermediates used in the production of such steroids, and to the production of such intermediates themselves. The specification is particularly concerned with the production of such steroids having anti-inflammatory action, e.g. beclomethasone dipropionate. There is disclosed a new route for preparing 9.alpha.halo-11.beta.-hydroxy-corticosteroids which involves the formation of novel 9.beta.,11.beta.-epoxy steroids which themselves may be conveniently obtained from the corresponding 9.alpha.-bromo-11.beta.-hydroxy-corticosteroids.
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There is disclosed a new route for preparing 9.alpha.halo-11.beta.-hydroxy-corticosteroids which involves the formation of novel 9.beta.,11.beta.-epoxy steroids which themselves may be conveniently obtained from the corresponding 9.alpha.-bromo-11.beta.-hydroxy-corticosteroids.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>1980</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19800930&amp;DB=EPODOC&amp;CC=CA&amp;NR=1086715A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19800930&amp;DB=EPODOC&amp;CC=CA&amp;NR=1086715A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TORABI, HOUSHANG</creatorcontrib><creatorcontrib>MORROW, DUANE F</creatorcontrib><creatorcontrib>LEVINSKY, HENRY L</creatorcontrib><title>STEROIDS</title><description>This specification relates to the production of 9.alpha.-halo-11.beta.-hydroxy-corticosteroids, to intermediates used in the production of such steroids, and to the production of such intermediates themselves. 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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title STEROIDS
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