PREPARATION OF PHENYLALKANOYLAMINES

3-R1-(phenyl)-CO!-phenyl-lower-alkanoylamines useful ln preparing N-{R1-(phenyl)-C(H)(OH)!-phenyl-lower-alkyl}amines having anti-inflammatory utility, whoreln R1 is hydrogen or 1 or 2 substituents. The alkanoylamines of the invention can be prepared by the reaction of a 3-R1-(phonyl)-CO!-phenylalkan...

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Bibliographische Detailangaben
1. Verfasser: ZENITZ, BERNARD L
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:3-R1-(phenyl)-CO!-phenyl-lower-alkanoylamines useful ln preparing N-{R1-(phenyl)-C(H)(OH)!-phenyl-lower-alkyl}amines having anti-inflammatory utility, whoreln R1 is hydrogen or 1 or 2 substituents. The alkanoylamines of the invention can be prepared by the reaction of a 3-R1-(phonyl)-CO!-phenylalkanoyl halide with an amine. 3-¢R1-(phenyl)-CO!-phenyl-lower-alkanoylamines useful ln preparing N-{¢R1-(phenyl)-C(H)(OH)!-phenyl-lower-alkyl}amines having anti-inflammatory utility, whoreln R1 is hydrogen or 1 or 2 substituents. The alkanoylamines of the invention can be prepared by the reaction of a 3-¢R1-(phonyl)-CO!-phenylalkanoyl halide with an amine.