PROCESS FOR PREPARING 1-ETHYL-2-/2'-METHOXY-5'-SULPHONAMIDOBENZOYL/-AMINOMETHYLPYRROLIDINE ITS SALTS

PROCESS FOR PREPARING 1-ETHYL-2-/2'-METHOXY-5'-SULPHONAMIDOBENZOYL/-AMINOMETHYLPYRROLIDINE ITS SALTS

1- Ethyl-2-(2'-methoxy-5'-sulphonamidobenzoyl)-amino-methyl-pyrrolidine of formula I (I) and the acid-addition salts thereof are prepared by a) reacting an acid-amide derivative of formula II (II) with a metal methoxide, or b) reacting a reactive derivative of 2-chloro-5-sulphonamidobenzoi...

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Bibliographische Detailangaben
Hauptverfasser: EGGENHOFER, JUDIT (NEE SZAUER), KOSARY, JUDIT, BALOGH, TIBOR, ORBAN, ERNOE, KASZTREINER, ENDRE, PAP, VERONIKA, KOCZKA, EVA (NEE FALTA), BORVENDEG, JANOS, FARKAS, LAJOS, SOMOGYI, GYOERGY, BURSICS, ERZSEBET (NEE SZEKERES)
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:1- Ethyl-2-(2'-methoxy-5'-sulphonamidobenzoyl)-amino-methyl-pyrrolidine of formula I (I) and the acid-addition salts thereof are prepared by a) reacting an acid-amide derivative of formula II (II) with a metal methoxide, or b) reacting a reactive derivative of 2-chloro-5-sulphonamidobenzoic acid with 1-ethyl-2-aminomethyl-pyrrolidine, and then reacting the obtained acid-amide derivative with a metal methoxide. The obtained compound possesses a significant psychotropic and gastric ulcer inhibiting effect.