PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE

PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE

The present invention relates to thiene diazoepinone derivatives useful as pharmacological agents having the formula (I) wherein each of R1 and R2 is a hydrogen atom, a straight or branch chain alkyl radical having 1 to 4 carbon atoms or R1 and R2 together form a tetramethylene chain and R3 is a phe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: TAPIA, ALVARO GARCIA, BRANA, MIGUEL FERNANDEZ, ROLDAN, CRISTOBAL MARTINEZ, ZAMBRANA, JOAQUIN DEL RIO, BARRACHINA, ANTONIO VILA CORO, PELAEZ, RAMON MADRONERO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator TAPIA, ALVARO GARCIA
BRANA, MIGUEL FERNANDEZ
ROLDAN, CRISTOBAL MARTINEZ
ZAMBRANA, JOAQUIN DEL RIO
BARRACHINA, ANTONIO VILA CORO
PELAEZ, RAMON MADRONERO
description The present invention relates to thiene diazoepinone derivatives useful as pharmacological agents having the formula (I) wherein each of R1 and R2 is a hydrogen atom, a straight or branch chain alkyl radical having 1 to 4 carbon atoms or R1 and R2 together form a tetramethylene chain and R3 is a phenyl group which may be substituted by a chloro nitro or trichloromethyl group or a pharmaceutically acceptable salt. The compounds may be prepared by reacting a 2-amino-3-aroyl-thiopene of the formula wherein R1, R2 and R3 are as above with oxazolidine-2,5-dione in the presence of hydrogen chloride and a solvent.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA1053228A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA1053228A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA1053228A3</originalsourceid><addsrcrecordid>eNrjZLAMCPJ3dnUJDXJVcPMPUggIcg1wDPL0c1dwcQ3yDHMM8QxzDVbwd1MI8fB09fN38XSM8ncN8PTz93PlYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo6GBqbGRkYWjsaEVQAAFPooKw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE</title><source>esp@cenet</source><creator>TAPIA, ALVARO GARCIA ; BRANA, MIGUEL FERNANDEZ ; ROLDAN, CRISTOBAL MARTINEZ ; ZAMBRANA, JOAQUIN DEL RIO ; BARRACHINA, ANTONIO VILA CORO ; PELAEZ, RAMON MADRONERO</creator><creatorcontrib>TAPIA, ALVARO GARCIA ; BRANA, MIGUEL FERNANDEZ ; ROLDAN, CRISTOBAL MARTINEZ ; ZAMBRANA, JOAQUIN DEL RIO ; BARRACHINA, ANTONIO VILA CORO ; PELAEZ, RAMON MADRONERO</creatorcontrib><description>The present invention relates to thiene diazoepinone derivatives useful as pharmacological agents having the formula (I) wherein each of R1 and R2 is a hydrogen atom, a straight or branch chain alkyl radical having 1 to 4 carbon atoms or R1 and R2 together form a tetramethylene chain and R3 is a phenyl group which may be substituted by a chloro nitro or trichloromethyl group or a pharmaceutically acceptable salt. The compounds may be prepared by reacting a 2-amino-3-aroyl-thiopene of the formula wherein R1, R2 and R3 are as above with oxazolidine-2,5-dione in the presence of hydrogen chloride and a solvent.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790424&amp;DB=EPODOC&amp;CC=CA&amp;NR=1053228A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19790424&amp;DB=EPODOC&amp;CC=CA&amp;NR=1053228A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAPIA, ALVARO GARCIA</creatorcontrib><creatorcontrib>BRANA, MIGUEL FERNANDEZ</creatorcontrib><creatorcontrib>ROLDAN, CRISTOBAL MARTINEZ</creatorcontrib><creatorcontrib>ZAMBRANA, JOAQUIN DEL RIO</creatorcontrib><creatorcontrib>BARRACHINA, ANTONIO VILA CORO</creatorcontrib><creatorcontrib>PELAEZ, RAMON MADRONERO</creatorcontrib><title>PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE</title><description>The present invention relates to thiene diazoepinone derivatives useful as pharmacological agents having the formula (I) wherein each of R1 and R2 is a hydrogen atom, a straight or branch chain alkyl radical having 1 to 4 carbon atoms or R1 and R2 together form a tetramethylene chain and R3 is a phenyl group which may be substituted by a chloro nitro or trichloromethyl group or a pharmaceutically acceptable salt. The compounds may be prepared by reacting a 2-amino-3-aroyl-thiopene of the formula wherein R1, R2 and R3 are as above with oxazolidine-2,5-dione in the presence of hydrogen chloride and a solvent.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAMCPJ3dnUJDXJVcPMPUggIcg1wDPL0c1dwcQ3yDHMM8QxzDVbwd1MI8fB09fN38XSM8ncN8PTz93PlYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo6GBqbGRkYWjsaEVQAAFPooKw</recordid><startdate>19790424</startdate><enddate>19790424</enddate><creator>TAPIA, ALVARO GARCIA</creator><creator>BRANA, MIGUEL FERNANDEZ</creator><creator>ROLDAN, CRISTOBAL MARTINEZ</creator><creator>ZAMBRANA, JOAQUIN DEL RIO</creator><creator>BARRACHINA, ANTONIO VILA CORO</creator><creator>PELAEZ, RAMON MADRONERO</creator><scope>EVB</scope></search><sort><creationdate>19790424</creationdate><title>PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE</title><author>TAPIA, ALVARO GARCIA ; BRANA, MIGUEL FERNANDEZ ; ROLDAN, CRISTOBAL MARTINEZ ; ZAMBRANA, JOAQUIN DEL RIO ; BARRACHINA, ANTONIO VILA CORO ; PELAEZ, RAMON MADRONERO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA1053228A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1979</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>TAPIA, ALVARO GARCIA</creatorcontrib><creatorcontrib>BRANA, MIGUEL FERNANDEZ</creatorcontrib><creatorcontrib>ROLDAN, CRISTOBAL MARTINEZ</creatorcontrib><creatorcontrib>ZAMBRANA, JOAQUIN DEL RIO</creatorcontrib><creatorcontrib>BARRACHINA, ANTONIO VILA CORO</creatorcontrib><creatorcontrib>PELAEZ, RAMON MADRONERO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAPIA, ALVARO GARCIA</au><au>BRANA, MIGUEL FERNANDEZ</au><au>ROLDAN, CRISTOBAL MARTINEZ</au><au>ZAMBRANA, JOAQUIN DEL RIO</au><au>BARRACHINA, ANTONIO VILA CORO</au><au>PELAEZ, RAMON MADRONERO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE</title><date>1979-04-24</date><risdate>1979</risdate><abstract>The present invention relates to thiene diazoepinone derivatives useful as pharmacological agents having the formula (I) wherein each of R1 and R2 is a hydrogen atom, a straight or branch chain alkyl radical having 1 to 4 carbon atoms or R1 and R2 together form a tetramethylene chain and R3 is a phenyl group which may be substituted by a chloro nitro or trichloromethyl group or a pharmaceutically acceptable salt. The compounds may be prepared by reacting a 2-amino-3-aroyl-thiopene of the formula wherein R1, R2 and R3 are as above with oxazolidine-2,5-dione in the presence of hydrogen chloride and a solvent.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre
recordid cdi_epo_espacenet_CA1053228A
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCEDURE FOR PREPARING DERIVATIVES OF THIENODIAZOEPINONE
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T07%3A38%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TAPIA,%20ALVARO%20GARCIA&rft.date=1979-04-24&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA1053228A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true