PROCESS FOR THE PRODUCTION OF 1-ORGANYL-SILATRANES AND CARBOFUNCTIONAL DERIVATIVES THEREOF
A process for the production of 1-organylsilatranes and their carbofunctional derivatives of the general formula X - Z - Si(OR)3N, where R = -CH2CH2- or -CH(CH3)CH2-; Z is a bivalent hydrocarbon radical; X = H, alkyl, aryl, F, Cl, Br, I, CF3, CN, NH2, SH, CNS, R1M, (R2O) 2P(O) or R3C(O)M, where R1 i...
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Zusammenfassung: | A process for the production of 1-organylsilatranes and their carbofunctional derivatives of the general formula X - Z - Si(OR)3N, where R = -CH2CH2- or -CH(CH3)CH2-; Z is a bivalent hydrocarbon radical; X = H, alkyl, aryl, F, Cl, Br, I, CF3, CN, NH2, SH, CNS, R1M, (R2O) 2P(O) or R3C(O)M, where R1 is alkyl, aryl, aralkyl or alkaryl; M = O or S; R is alkyl; and R3 is alkyl, aryl, RF (a carbon- tetra- fluoride chain containing from 1 to 10 carbon atoms) or A-C6H4OCH2, where A is halogen, an alkyl group or an alkoxy group, which comprises reacting triethanolamine or its derivatives of the general formula N(ROH)3 , where R = -CH2CH2- or -CH(CH3)CH2-, with 1-organlytrialkoxysilanes of the general formula X - Z - Si(OR4)3, where R is alkyl; X = H, alkyl, aryl, I, Br, Cl, F, CF3, CN, NH2,SH, CNS, R1M, (R2O)2P(O) or R3C(O)M, where R1 is alkyl, aryl, aralkyl or alkaryl; M = O or S; R2 is alkyl; and R3 is alkyl, aryl, RF (a carbon-tetralucride chain containing from 1 to 10 carbon atoms) or, A-C6H4OCH2, where A is halogen, an alkyl group or an alkoxy group, in the presence of a low-boiling polar organic solvent or a low-boiling polar organic solvent combined with an alkali catalyst or an alkali catalyst, and subsequently recovering the desired product, and, should the process be conducted in the presence of a low-boiling polar organic solvent, triethanolamine or its derivatives are initially admixed with said solvent, after which a 1-organyltrialkoxysilane is added to the reaction mixture. Said compounds find application in medicine for treating wounds, ulcers, burns and dermatites, as antiallergic drugs for the prevention and treatment of certain forms of baldness, as specific biostimulants in animal husbandry and poultry breeding, as plant growth regulation agents, as additions to synthetic polymers, and also as intermediate products in organic synthesis. |
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