1-ARYL-N-DIALKYLAMINOALKYL-3,4-DIHYDRO-2 (1H)-ISOQUINOLINECARBOXAMIDES AND RELATED COMPOUNDS

1-ARYL-N-DIALKYLAMINOALKYL-3,4-DIHYDRO-2 (1H)-ISOQUINOLINECARBOXAMIDES AND RELATED COMPOUNDS

1-Aryl-N-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related N-substituted amides having anti-arrhythmic, anti-bacterial, anti-fungal, antialgal and anthelmintic activity are described herein. The subject compounds can be prepared by reacting the appropriate 3,4-dihydro-2(1H)-is...

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Bibliographische Detailangaben
1. Verfasser: YONAN, PETER K
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:1-Aryl-N-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related N-substituted amides having anti-arrhythmic, anti-bacterial, anti-fungal, antialgal and anthelmintic activity are described herein. The subject compounds can be prepared by reacting the appropriate 3,4-dihydro-2(1H)-isoquinolinecarbonyl chloride with a dialkylaminoalkylamine or similar compound, or by reacting an N-(chloroalkyl)-3,4-dihydro-2(1H)-isoquinoline-carboxamide with the appropriate dialkylamine or similar compound.