PHARMACEUTICAL COMPOSITIONS CONTAINING P-HYDROXYACETANILIDE

1463505 Pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORP 7 Nov 1974 [21 Nov 1973] 54098/73 Heading A5B Pharmaceutical compositions comprising the analgesic and antipyretic p-hydroxyacetanilide (acetaminophen, paracetamol) and L- cysteine or a compound which is converted thereto in vivo or a salt thereof such as a sulphur-containing amino acid or a peptide containing such an amino acid as a unit thereof e.g. cystine, methionine, L-glutamyl-L-cysteine and L-cysteinyl glycine directly counter the toxicity of an overdose, of the p-hydroxyacetanilide without reducing its normal beneficial action. The compositions may be administered orally in the form of tablets or elixirs and may also contain caffeine, caffeine hydrate, codeine, codeine phosphate, dihydrocodeine tartrate, pseudoephedrine hydrochloride and/or phenolphthalein.