MICROENCAPSULATED MEDICAL POWDERS

1403584 Encapsulated antibiotics BEECHAM GROUP LTD 16 May 1973 [19 May 1972] 23576/72 Heading A5B A powder useful in the formulation of pharmaceutical preparations consists essentially of "microcapsules" having an average diameter of 100Á to 300u, at least 90% of the microcapsules having d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
1. Verfasser:	SEAGER, HARRY
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR RELEVANT APPARATUS TRANSPORTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	1403584 Encapsulated antibiotics BEECHAM GROUP LTD 16 May 1973 [19 May 1972] 23576/72 Heading A5B A powder useful in the formulation of pharmaceutical preparations consists essentially of "microcapsules" having an average diameter of 100Á to 300u, at least 90% of the microcapsules having diameters in the range 75u to 450Á and which comprises 98% to 99.9% of a #-lactam antibiotic coated by 0.17 to 2% of polyvinylpyrrolidone. The term "microcapsule" means a particle composed of an outer, generally porous shell of PVP as coating agent with an inner core of fine particles. They may be made by spray-drying a slurry of antibiotic in a solution of PVP in a suitable solvent. Many conventional solid and liquid formulations comprising the microcapsules are mentioned. Specified antibiotics include; ampicillin, amoxicillin, isoxazolylpenicillin, salts and esters thereof and esters of ampicillin and carbenicillin.