INTERMEDIATES FOR THE PREPARATION OF NEW A-UAMINOPENICILLINS

Title cpds. have formula: (where R is 2-7c alkyl, R2R3-substd. phenyl (where R2 is H or OH and R3 is H or halogen such as Cl or F, theinyl or furyl), R1 is -CHMeOCOR4, -CHR5OCOOR4 or -CH2NHCOOR4 or -CH2NHCOOR4 where R4 is 1-4C alkyl and R5 is H, Me or Et), pref. cpd. has R = Ph, R1 = CHMe.OAc. The c...

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Hauptverfasser:	SJOEBERG, BERNDT O.H, EKSTROEM, BERTIL A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Title cpds. have formula: (where R is 2-7c alkyl, R2R3-substd. phenyl (where R2 is H or OH and R3 is H or halogen such as Cl or F, theinyl or furyl), R1 is -CHMeOCOR4, -CHR5OCOOR4 or -CH2NHCOOR4 or -CH2NHCOOR4 where R4 is 1-4C alkyl and R5 is H, Me or Et), pref. cpd. has R = Ph, R1 = CHMe.OAc. The cpds. are rapidly hydrolysed in blood serum to corresp. aminopenicillins.