derivados de 1,2,4-triazolo[4,3-a]piridina e seu uso como moduladores alostéricos positivos de recpetores de mglur2

wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2"), which are useful for the treatment or prevention of neurological and psychiatric disorders associated...

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Hauptverfasser: GREGOR JAMES MACDONALD, JUAN ANTONIO VEGA RAMIRO, ANDRÉS AVELINO TRABANCO-SUAREZ, JOSÉ MARIA CID-NUNEZ, DANIEL OEHLRICH, GARY JOHN TRESADERN
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Sprache:por
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Zusammenfassung:wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2"), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.