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A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Catherine A. Bothof, Kannan Seshadri, Clinton P. Waller JR, Douglas E. Weiss
Format: Patent
Sprache:por
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Beschreibung
Zusammenfassung:A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.