composicoes de peptideos profarmacos de alta penetracao e compostos relacionados a peptideos

A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide o...

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Hauptverfasser: YUHUA CHEN, CHONGXI YU, SHIQIAN TU, BINBING YAN, LINA XU
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creator YUHUA CHEN
CHONGXI YU
SHIQIAN TU
BINBING YAN
LINA XU
description A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title composicoes de peptideos profarmacos de alta penetracao e compostos relacionados a peptideos
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