composicoes de peptideos profarmacos de alta penetracao e compostos relacionados a peptideos

A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YUHUA CHEN, CHONGXI YU, SHIQIAN TU, BINBING YAN, LINA XU
Format: Patent
Sprache:por
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A high penetration composition or high penetration prodrugs of peptide or peptide-related compound comprising functional unit, linker, and transportational unit are provided. The functional unit is covalently linked to the transportational unit via the linker, and comprises a moiety of the peptide or the peptide-related compound. The transportational unit comprises protonatable amine group. The linker comprises chemical bond that is capable of being cleaved after the composition penetrates across a biological barrier.