suspensões aquosas de riluzol

Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DANIELE BARBARESCHI, MARCO ADAMI, PAOLO MASCAGNI, ROBERTA ARTICO, TIZIANO OLDONI, JAIME MOSCOSO
Format: Patent
Sprache:por
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Beschreibung
Zusammenfassung:Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v and has an average particle size lower than 200 µm; such suspensions are devoided of the known local (mouth) anaesthetic effects of riluzole.