oligonucleotídeo antissenso, composição que compreende o mesmo e uso do dito oligonucleotídeo para tratar distrofia muscular

compostos, composições e seus usos para induzir o salto de éxon em dmd são fornecidos moléculas antissentido capazes de se ligarem a um sítio alvo selecionado no gene da distrofina humana para induzir o salto de éxon, e métodos de utilização dos mesmos para o tratamento de distrofia muscular. Provid...

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Hauptverfasser:	RYSZARD KOLE, PETER SAZANI
Format:	Patent
Sprache:	por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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creator	RYSZARD KOLE PETER SAZANI
description	compostos, composições e seus usos para induzir o salto de éxon em dmd são fornecidos moléculas antissentido capazes de se ligarem a um sítio alvo selecionado no gene da distrofina humana para induzir o salto de éxon, e métodos de utilização dos mesmos para o tratamento de distrofia muscular. Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof to treat muscular dystrophy.
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title	oligonucleotídeo antissenso, composição que compreende o mesmo e uso do dito oligonucleotídeo para tratar distrofia muscular
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