métodos para purificação de moléculas de ligação a antígeno de domínio único

métodos para purificação de moléculas de ligação a antígeno de domínio único

Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based...

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Bibliographische Detailangaben
Hauptverfasser: AUSTIN WAYNE BOESCH, PAUL R. BROWN, ANDREW M. WOOD, SCOTT ANDREAS TOBLER
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:Processes and methods of purifying or separating Single Domain Antigen Binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.