novos heterociclos

Pyrimidine compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof, are useful are useful as PDE4 inhibitors and are useful for...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Bhakiaraj, Durairaj, Peter, Kachhadia, Virendra, Janarthanam, Venkatesan, Gadde, Sathyanarayana, Saxena, Sanjeev, Surendran, Narayanan, Sharma, Ganapavarapu, Veera, Raghava, Rajagopal, Sriram, Narayanan, Sukunath, Tadiparthi, Ravikumar, Narayanam, Maruthikumar, Parameswaran, Venkatesan, Vishwakarma, Lolaknath, Santosh, Sappanimuthu, Thirunavukkarasu, Balasubramanian, Gopalan, Narasimhan, Kilambi, Thara, Sathya, Narayana, Ramachandran, Uma, Narayanan, Shridhar, Reddy, Gaddam, Om, Srinivas, Visweswara, Akella, Staya, Surya
Format:	Patent
Sprache:	por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Pyrimidine compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof, are useful are useful as PDE4 inhibitors and are useful for treating PDE4 mediated diseases and in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; ARDS; psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever.