imunoterápico de cd7 e combinação com quimioterápico bifuncional deste

The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that ca...

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Hauptverfasser: CHRISTY ANNE NILSSON, PHILIP TAN, MARTHA S. HAYDEN-LEDBETTER, JEFFREY A. LEDBETTER, CHARLES G. CERVENY, CECILE MORALES, PETER ARMSTRONG THOMPSON, WILLIAM BRADY, SANDY ALEXANDER SIMON
Format: Patent
Sprache:por
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Zusammenfassung:The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B-cell related autoimmune, inflammatory, or hyperproliferative diseases.