composto para tratamento da dor

The present invention relates to a compound of formula (I) wherein X is hydrogen, R1, R1C(O), R1CO2, or a COX2 inhibitor, wherein R1 is C1-20 alkyl, aryl, arylalkyl, alkyloxy or arylalkyloxy; wherein Y is OR2, NHR3N(R3)2, or a COX inhibitor; wherein R2 is hydrogen or C1-20 alkyl and each R3 is indep...

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Bibliographische Detailangaben
Hauptverfasser:	SUKALYAN CHATTERJEE, ANA DULCE ASCENSÃO CORREIA, MANUEL NUNO DE SOUZA SIMÕES DE MEL, EDUARDO BARDAJÍ RODRIGUEZ, HELENA MARGARIDA MOREIRA DE OLIVEIRA VIEIRA, MARTA SOFIA CARVALHO TEIXEIRA PINTO, CHRISTOPHE FRANÇOIS AIMÉ ROCA, MARTA ISABEL HEITOR CEREJO, MONTSERRAT HERAS COROMINAS, PATRÍCIA RAMALHETE MENDES DA SILVA CALADO, MIGUEL AUGUSTO RICO BOTAS CASTANHO, MARTA MARIA BATISTA ROBEIRO, JOSÉ MANUEL BERNARDO DE SOUZA
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a compound of formula (I) wherein X is hydrogen, R1, R1C(O), R1CO2, or a COX2 inhibitor, wherein R1 is C1-20 alkyl, aryl, arylalkyl, alkyloxy or arylalkyloxy; wherein Y is OR2, NHR3N(R3)2, or a COX inhibitor; wherein R2 is hydrogen or C1-20 alkyl and each R3 is independently hydrogen or a C1-4 alkyl; wherein T is OR4, NHR5N(R5)2, or a COX inhibitor wherein R4 is hydrogen or C1-20 alkyl and each R5 is independently hydrogen or a C1-4 alkyl; wherein Z is hydrogen, R6, R6C(O), R6CO2, or a COX2 inhibitor; wherein R6 is C1-20 alkyl, aryl, arylalkyl, alkyloxy or arylalkyloxy; with the proviso wherein when X and Z are hydrogen and T is OH, Y is not OH; for use in the prevention and/or treatment of pain wherein said compound is provided for systemic administration.