ativadores de pirrolidinona glicoquinase

ativadores de pirrolidinona glicoquinase são proporcionados compostos da fórmula (i) : em que x, r1 , r2 e r3 são conforme definidos no relatório descritivo, bem corno sais farrnaceuticarnente aceitáveis destes. esses compostos e as composições farmacêuticas contendo os mesmos são úteis no tratament...

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Bibliographische Detailangaben
Hauptverfasser:	Ramakanth Sarabu, Robert Francis Kester, Yimin Qian, John A. Brinkman, Jefferson Wright Tilley, Nancy-Ellen Haynes, Stuart Hayden, Steven Joseph Berthel, Nathan Robert Scott, Lee Apostle Mcdermott
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	ativadores de pirrolidinona glicoquinase são proporcionados compostos da fórmula (i) : em que x, r1 , r2 e r3 são conforme definidos no relatório descritivo, bem corno sais farrnaceuticarnente aceitáveis destes. esses compostos e as composições farmacêuticas contendo os mesmos são úteis no tratamento de doenças ou dist úrbios metabólicos tais corno , por exemplo, diabetes rnelito tipo ii . Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.