Compostos derivados de pirazolo[1,5-a] piprimidinas heterocíclicos bicíclicos ou heterocíclicos espiro bicíclicos em ponte, seus métodos de preparação e usos, e composição farmacêutica

Compostos derivados de pirazolo[1,5-a] piprimidinas heterocíclicos bicíclicos ou heterocíclicos espiro bicíclicos em ponte, seus métodos de preparação e usos, e composição farmacêutica

Compounds of formula A: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.

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Bibliographische Detailangaben
Hauptverfasser: MINU DHANJISH DUTIA, JEREMY IAN LEVIN, DAN MAARTEN BERGER, MARTIN JOSEPH GRANDI, DARRIN WILLIAM HOPPER, NANCY TORRES, XIAOLUN WANG, CHUNCHUN ZHANG, ALEJANDRO LEE DUNNICK
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compounds of formula A: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.