ácido rubonucleicos de pequena interferência (sirna) catiônicos, composições farmacêuticas, aplicação de ácidos rubonucleicos de pequena interferência (sirna) catiônicos e processo de síntese automatizado de um filamento de ácido rubonucleico de pequena interferência (sirna) catiônico

The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of t...

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Bibliographische Detailangaben
Hauptverfasser: Jean-Serge Remy, Mitsuharu Kotera, Nadége Pfender, Jean-Paul Behr
Format: Patent
Sprache:por
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Zusammenfassung:The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.