Derivado esteroide de gama-lactona de ácido 17-hidróxi-19-nor-21-carboxílico, uso do mesmo e medicamento que contém o derivado
The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the...
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| creator | HANS PETER MUHN STEFFEN BORDEN FREDERIK MENGES KATJA PRELLE THOMAS FRENZEL ROLF BOHLMANN SVEN RING JAN HÜBNER ULRICH KLAR JOACHIM KUHNKE |
| description | The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action. |
| format | Patent |
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The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</description><language>por</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150616&DB=EPODOC&CC=BR&NR=PI0821922A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150616&DB=EPODOC&CC=BR&NR=PI0821922A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HANS PETER MUHN</creatorcontrib><creatorcontrib>STEFFEN BORDEN</creatorcontrib><creatorcontrib>FREDERIK MENGES</creatorcontrib><creatorcontrib>KATJA PRELLE</creatorcontrib><creatorcontrib>THOMAS FRENZEL</creatorcontrib><creatorcontrib>ROLF BOHLMANN</creatorcontrib><creatorcontrib>SVEN RING</creatorcontrib><creatorcontrib>JAN HÜBNER</creatorcontrib><creatorcontrib>ULRICH KLAR</creatorcontrib><creatorcontrib>JOACHIM KUHNKE</creatorcontrib><title>Derivado esteroide de gama-lactona de ácido 17-hidróxi-19-nor-21-carboxílico, uso do mesmo e medicamento que contém o derivado</title><description>The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjb0KwjAUhbs4iPoOwdmAjYN29BfdRNzLNblqoMmtSSqdfRNHBycfoS9mhD6AcODjwMc53eSxQqfvoIihD-hIK2QxFzDAC5CBLPx685Q6OumUX7VyzafWPM24JcdFyiW4E9XNu9CSRqzyxKJq0Js4Gqm0BIM2ELtVyCTZ0LwMi1L73E86Zyg8Dlr2kuFmfVxuOZaUoy9BosWQLw773Xgm0kyIuZj8JX0BmdFLMw</recordid><startdate>20150616</startdate><enddate>20150616</enddate><creator>HANS PETER MUHN</creator><creator>STEFFEN BORDEN</creator><creator>FREDERIK MENGES</creator><creator>KATJA PRELLE</creator><creator>THOMAS FRENZEL</creator><creator>ROLF BOHLMANN</creator><creator>SVEN RING</creator><creator>JAN HÜBNER</creator><creator>ULRICH KLAR</creator><creator>JOACHIM KUHNKE</creator><scope>EVB</scope></search><sort><creationdate>20150616</creationdate><title>Derivado esteroide de gama-lactona de ácido 17-hidróxi-19-nor-21-carboxílico, uso do mesmo e medicamento que contém o derivado</title><author>HANS PETER MUHN ; STEFFEN BORDEN ; FREDERIK MENGES ; KATJA PRELLE ; THOMAS FRENZEL ; ROLF BOHLMANN ; SVEN RING ; JAN HÜBNER ; ULRICH KLAR ; JOACHIM KUHNKE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0821922A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>HANS PETER MUHN</creatorcontrib><creatorcontrib>STEFFEN BORDEN</creatorcontrib><creatorcontrib>FREDERIK MENGES</creatorcontrib><creatorcontrib>KATJA PRELLE</creatorcontrib><creatorcontrib>THOMAS FRENZEL</creatorcontrib><creatorcontrib>ROLF BOHLMANN</creatorcontrib><creatorcontrib>SVEN RING</creatorcontrib><creatorcontrib>JAN HÜBNER</creatorcontrib><creatorcontrib>ULRICH KLAR</creatorcontrib><creatorcontrib>JOACHIM KUHNKE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HANS PETER MUHN</au><au>STEFFEN BORDEN</au><au>FREDERIK MENGES</au><au>KATJA PRELLE</au><au>THOMAS FRENZEL</au><au>ROLF BOHLMANN</au><au>SVEN RING</au><au>JAN HÜBNER</au><au>ULRICH KLAR</au><au>JOACHIM KUHNKE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Derivado esteroide de gama-lactona de ácido 17-hidróxi-19-nor-21-carboxílico, uso do mesmo e medicamento que contém o derivado</title><date>2015-06-16</date><risdate>2015</risdate><abstract>The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS |
| title | Derivado esteroide de gama-lactona de ácido 17-hidróxi-19-nor-21-carboxílico, uso do mesmo e medicamento que contém o derivado |
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