Protease, método para o tratamento de doenças, e, uso de uma protease

The invention relates to novel variants of a protease derived from Nocardiopsis sp. (SEQ ID NO: 1) and closely related proteases, as well as their pharmaceutical use. The variants show improved performance in the treatment of pancreatic exocrine insufficiency (PEI). The variants may be combined with...

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Hauptverfasser: ALLAN SVENDSEN, PETER COLIN GREGORY, SIGNE ESKILDSEN LARSEN, THOMAS LENHARD, LARS BEIER, TANJA MARIA ROSENKILDE KJAER
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creator ALLAN SVENDSEN
PETER COLIN GREGORY
SIGNE ESKILDSEN LARSEN
THOMAS LENHARD
LARS BEIER
TANJA MARIA ROSENKILDE KJAER
description The invention relates to novel variants of a protease derived from Nocardiopsis sp. (SEQ ID NO: 1) and closely related proteases, as well as their pharmaceutical use. The variants show improved performance in the treatment of pancreatic exocrine insufficiency (PEI). The variants may be combined with a lipase and/or an amylase. Other examples of medical indications are: Treatment of digestive disorders, pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Protease, método para o tratamento de doenças, e, uso de uma protease
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