Cis-imidazolinas quirais

There are provided compounds of the formula or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V 3 , V 2 , R 1 , R 2 , R 3 , R 4 and R 5 are as herein described, processes for obtaining said compounds and pharmaceutical preparations containing them. These compounds are useful as anti...

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Bibliographische Detailangaben
Hauptverfasser:	DAVID JOSEPH BARTKOVITZ, HONGJU LI, ALLEN JOHN LOVEY, BINH THANH VU, XIN-JIE CHU, JIANPING CAI, CHUNLIN ZHAO
Format:	Patent
Sprache:	por
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	There are provided compounds of the formula or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V 3 , V 2 , R 1 , R 2 , R 3 , R 4 and R 5 are as herein described, processes for obtaining said compounds and pharmaceutical preparations containing them. These compounds are useful as anticancer agents, in particular as agents in the treatment of solid tumors.