COMPOSIÇÕES E MÉTODOS QUE EMPREGAM ANTAGONISTAS NMDA PARA ALCANÇAR UM EFEITO POUPADOR DE ANESTÉSICO

COMPOSIÇÕES E MÉTODOS QUE EMPREGAM ANTAGONISTAS NMDA PARA ALCANÇAR UM EFEITO POUPADOR DE ANESTÉSICO

Provided herein are compositions, combinations, and methods comprising NMDA antagonists including, but not limited to, NMDA glutamate receptor antagonists such as [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1-(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof, which are effective in reducing the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DAVID ROBERT HUSTEAD, CECIL MARK EPPLER, WILLIAM W. MUIR III, RAPHAEL JOHANNES GERHARDUS ZWIJNENBERG, THOMAS GERARD CULLEN
Format: Patent
Sprache:por
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are compositions, combinations, and methods comprising NMDA antagonists including, but not limited to, NMDA glutamate receptor antagonists such as [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1-(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof, which are effective in reducing the amount of anesthetic required to maintain anesthesia (i.e. to achieve an anesthetic-sparing effect).