PROCESSO PARA A PREPARAÇÃO DE DERIVADOS SEMISSINTÉTICOS DE BETA-LACTAMA

The present invention describes a process for the synthesis of a semi-synthetic beta-lactam compound from a nucleus and a side chain selected from the group consisting of D-phenylglycine and D-dihydro-phenylglycine in the form of a side chain ester and an enzyme catalyzing the coupling of the side c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HAROLD MONRO MOODY, THEODORUS JOHANNES GODFRIED MARIA VAN DOOREN, THOMAS VAN DER DOES
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention describes a process for the synthesis of a semi-synthetic beta-lactam compound from a nucleus and a side chain selected from the group consisting of D-phenylglycine and D-dihydro-phenylglycine in the form of a side chain ester and an enzyme catalyzing the coupling of the side chain ester to the nucleus characterized in that the side chain ester is not isolated as a solid intermediate.