vacinas baseadas no direcionamento de antígeno ao dcir expresso em células apresentadoras de antígeno

The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gerard Zurawski, Jacques F. Banchereau
Format: Patent
Sprache:por
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Beschreibung
Zusammenfassung:The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.