COMPOSTO OU UM SAL DO MESMO, COMPOSIÇÃO FARMACÊUTICA, USO DE UM COMPOSTO OU UM SAL DO MESMO FARMACEUTICAMENTE ACEITÁVEL, MÉTODO PARA TRATAR DOENÇAS MEDIADAS POR GLK, E, PROCESSO PARA A PREPARAÇÃO DE UM COMPOSTO

COMPOSTO OU UM SAL DO MESMO, COMPOSIÇÃO FARMACÊUTICA, USO DE UM COMPOSTO OU UM SAL DO MESMO FARMACEUTICAMENTE ACEITÁVEL, MÉTODO PARA TRATAR DOENÇAS MEDIADAS POR GLK, E, PROCESSO PARA A PREPARAÇÃO DE UM COMPOSTO

The invention relates to a novel group of compounds of Formula (I) or a salt thereof: wherein R1, A and HET-1 are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK) such as type 2 diabetes. The in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEONIE CAMPBELL, KURT GORDON PIKE, ABID SULEMAN, MICHAEL JAMES WARING
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to a novel group of compounds of Formula (I) or a salt thereof: wherein R1, A and HET-1 are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK) such as type 2 diabetes. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by GLK using said compounds and methods for preparing compounds of Formula (I).