derivados de imidazol

derivados de imidazol

DERIVADOS DE IMIDAZOL . Compostos da fórmula (1), onde R1, R2, R3, R4 ,R5, R6, R7, R8, R9, R10, R11, X e X' têm os significados indicados na reivindicação 1, que são inibidores de tirosina quinases, em particular TIE-2 e Raf quinases, e podem ser empregados, inter alia, para o tratamento de tum...

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Hauptverfasser: MARTA SOLER RIERA, WOLFGANG STOHLE, ELISABET ROSELL-VIVES, JAUME ADAN, HELENE CRASSIER, ARNE SUTTER, FRANCESC MITJANS, ALFRED JONCZYK, GUENTER H÷LZEMANN, WILFRIED RAUTENBERG
Format: Patent
Sprache:por
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:DERIVADOS DE IMIDAZOL . Compostos da fórmula (1), onde R1, R2, R3, R4 ,R5, R6, R7, R8, R9, R10, R11, X e X' têm os significados indicados na reivindicação 1, que são inibidores de tirosina quinases, em particular TIE-2 e Raf quinases, e podem ser empregados, inter alia, para o tratamento de tumores. Compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, X and X' have the meanings indicated in claim 1 , are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.