Derivados de 1-(w-Ú3,4-dihidro-2-naftalenil)aquil¾ amina cíclica processo para a preparaç o dos mesmos e composiç o farmacêutica contendo os mesmos

1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene,...

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Hauptverfasser: AKI KANEHIRA, KAZUHISA AKIYAMA, TOSHIYA MORIE, ISAO SHIMIZU, NAOKI KAI, KATSUYOSHI KAWASHIMA, KATSUHIKO HINO
Format: Patent
Sprache:por
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Zusammenfassung:1-Ä omega -(3,4-Dihydro-2-naphthalenyl)alkylÜ cyclic amine derivatives represented by general formula (I) and salts and N-oxide derivatives thereof, wherein R and R represent each hydrogen, halogeno, hydroxy, alkyl, alkoxy, hydroxymethyl, etc., or R and R form together methylenedioxy, trimethylene, etc.; R represents hydrogen, etc.; R represents hydrogen, hydroxy, alkyl, etc.; R represents hydrogen, alkyl, etc.; p is an integer of from 2 to 6; and q is an integer of from 3 to 7; excluding the case where R , R , R , R and R are all hydrogen, p is 2 and q is 5. The compounds have a potent effect of suppressing urinary reflex and thus are useful as a remedy for frequent urination and urinary incontinence.