Biomateriais compósitos

biomateriais compósitos. a presente invenção se refere a biomateriais de scaffold compósitos incluindo duas ou mais subunidades de biomaterial de scaffold, cada uma incluindo um tecido vegetal ou fúngico descelularizado do qual materiais celulares e ácidos nucléicos do tecido são removidos, o tecido...

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Hauptverfasser:	ANDREW E. PELLING, SZERESZEWSKI KAMA, HICKEY RYAN, CAMPUZANO SANTIAGO, PAULA CRISTINA DE SOUSA FARIA TISCHER
Format:	Patent
Sprache:	por
Schlagworte:	ADDITIVE MANUFACTURING TECHNOLOGY ADDITIVE MANUFACTURING, i.e. MANUFACTURING OFTHREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVEAGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING,STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE ADHESIVES AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR DYES ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J GENERAL PROCESSES OF COMPOUNDING HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MUTATION OR GENETIC ENGINEERING NATURAL RESINS NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL ORGANIC MACROMOLECULAR COMPOUNDS PAINTS PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL POLISHES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SEPARATION SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES TRANSPORTING USE OF MATERIALS AS ADHESIVES VINEGAR WINE WORKING-UP
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Beschreibung
Zusammenfassung:	biomateriais compósitos. a presente invenção se refere a biomateriais de scaffold compósitos incluindo duas ou mais subunidades de biomaterial de scaffold, cada uma incluindo um tecido vegetal ou fúngico descelularizado do qual materiais celulares e ácidos nucléicos do tecido são removidos, o tecido vegetal ou fúngico descelularizado tendo uma estrutura porosa tridimensional, as duas ou mais subunidades de biomaterial de scaffold sendo montadas no biomaterial de scaffold compósito e mantidas unidas através de fundição com gel usando uma cola de hidrogel; através de geometria complementar de interligação das duas ou mais subunidades de biomaterial de scaffold; através de biolitografia baseada em montagem guiada (gad); através de reticulação química; ou qualquer combinação dos mesmos. também são fornecidos métodos para produzir esses biomateriais de scaffold, bem como métodos e usos dos mesmos. Provided herein are composite scaffold biomaterials including two or more scaffold biomaterial subunits, each including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure, the two or more scaffold biomaterial subunits being assembled into the composite scaffold biomaterial and held together via gel casting using a hydrogel glue; via complementary interlocking geometry of the two or more scaffold biomaterial subunits; via guided assembly based biolithography (GAB); via chemical cross-linking; or any combinations thereof. Methods for producing such scaffold biomaterials, as well as methods and uses thereof, are also provided.