hidrogenação catalítica de cianopiridinas substituídas e processo para preparar piridilmetilbenzamidas substituídas
The present invention relates to a novel catalytic hydrogenation of substituted cyanopyridine derivatives, wherein the substitution is present on the pyridine ring, in particular 3-chloro-2-cyano-5-trifluoromethylpyridine [= Py-CN] to the corresponding substituted 2-methylaminopyridine derivatives,...
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Sprache: | por |
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Zusammenfassung: | The present invention relates to a novel catalytic hydrogenation of substituted cyanopyridine derivatives, wherein the substitution is present on the pyridine ring, in particular 3-chloro-2-cyano-5-trifluoromethylpyridine [= Py-CN] to the corresponding substituted 2-methylaminopyridine derivatives, in particular 2-aminomethyl-3-chloro-5-trifluoromethylpyridine [= Py-methylamine] or salts thereof in the presence of metal catalysts such as in particular palladium catalysts, catalytic modifiers and acids. |
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