composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral

composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral

The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides...

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Hauptverfasser: XIAOLAN ZHOU, KEITH SOO-NYUNG KWAK, HUIQUAN HAN, LEI-TING TONY TAM, JEONGHOON SUN
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Sprache:por
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator XIAOLAN ZHOU
KEITH SOO-NYUNG KWAK
HUIQUAN HAN
LEI-TING TONY TAM
JEONGHOON SUN
description The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title composição farmacêutica, método para tratar um cancer e método para reduzir o tamanho de uma massa tumoral
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