inibição da expressão genética viral

this invention relates to modified short interfering rna (sirna) nucleic acid molecules, particularly sirna's which have been modified by the addition of a 2 -0- guanidinopropyl (gp) modified nucleoside. in particular the invention relates to modified sirnas which are capable of silencing targe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: STEFAN BERNHARDT, JOACHIM W. ENGELS, MAXIMILIAN C.R. BUFF, MUSA MARIMANI, ABDULLAH ELY, JENNIFER D'ONOFRIO, JUSTIN HEAN, JOLANTA BRZEZINSKA, PATRICK ARBUTHNOT
Format: Patent
Sprache:por
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