processo para a preparação de derivados de 2,2-difluoroetilamina partindo de n-(2,2-difluoroetil) - prop - 2 - eno - 1 - amina

processo para a preparação de derivados de 2,2-difluoroetilamina partindo de n-(2,2-difluoroetil) - prop - 2 - eno - 1 - amina

Process for the preparation of 2,2-difluoroethylamine derivatives of the formula (IV) comprising the steps (i) and (ii): step (i): reaction of N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (I) with a compound of the formula (II) A-CH2-E(II) to give a compound of the formula (III) optionally...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NOBERT LUI, JENS -DIETMAR HEINRICH
Format: Patent
Sprache:por
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Process for the preparation of 2,2-difluoroethylamine derivatives of the formula (IV) comprising the steps (i) and (ii): step (i): reaction of N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (I) with a compound of the formula (II) A-CH2-E(II) to give a compound of the formula (III) optionally in the presence of an inorganic or organic base, and step (ii): removal of the allyl group from the compound of the formula (III), in which, in the formulae (II), (III) and (IV), A and E have the meanings given in the description.