derivados de 2-amino-piriidina úteis como inibidores de jnk

Compounds of formula I or pharmaceutically acceptable salts thereof, wherein R5 is a group of formula (a) or (b): and wherein m, n, p, q, X, Y, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and...

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Hauptverfasser: LEYI GONG, BRADLEY E. LOE, DAVID MARK ROTSTEIN, HUMBERTO BARTOLOME ARZENO, LUBOV FILONOVA, YUNOU TAN, TANIA SILVA, ERIN M. O'BRIEN, WYLIE SOLANG PALMER, DAVID MICHAEL GOLDSTEIN
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Sprache:por
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Zusammenfassung:Compounds of formula I or pharmaceutically acceptable salts thereof, wherein R5 is a group of formula (a) or (b): and wherein m, n, p, q, X, Y, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. The compounds and compositions disclosed herein are useful to modulate the activity of JNK and treat diseases associated with JNK activity.