Agentes antibacterianos de ácido quinolino e naftiridino carboxìlico

"AGENTES ANTIBACTERIANOS DO áCIDO QUINOLINO E NAFTIRIDINO CARBOXìLICO". Compostos com a fórmula (I), ou seus sais ou prodrogas farmaceuticamente aceitáveis, de utilidade como agentes antibacterianos. Compounds having formula (I), or pharmaceutically acceptable salts or prodrugs thereof, wh...

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Hauptverfasser: JURGEN DINGES, BRIAN E. GREEN, LINDA M. LYNCH, COLLEEN C. SCHULTZ, CURT S. COOPER, STEVEN W. ELMORE, DOUGLAS K. HUTCHINSON, DAVID D. ANDERSON, PAMELA L. DONNER, QUINGHUA XIE
Format: Patent
Sprache:por
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Zusammenfassung:"AGENTES ANTIBACTERIANOS DO áCIDO QUINOLINO E NAFTIRIDINO CARBOXìLICO". Compostos com a fórmula (I), ou seus sais ou prodrogas farmaceuticamente aceitáveis, de utilidade como agentes antibacterianos. Compounds having formula (I), or pharmaceutically acceptable salts or prodrugs thereof, wherein A is nitrogen or (II), wherein W is selected from the group consisting of (1) hydrogen and (2) optionally substituted alkyl; A is selected from the group consisting of (1) -S-, (2) -O-, and (3) -N(R )-, wherein R is hydrogen or C1-C6 alkyl; and R and R together are a carbocyclic or a heterocyclic ring, are useful as antibacterial agents.