Peptídeo, processo de obtenção de peptídeo, formulação compreendendo peptídeo, método de prevenção de crescimento de parasitas, fungos e bactérias, método para inativar a endotoxina de bactérias gram-negativas

The invention refers to small peptides with low hemolytic activity, presenting similar antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a hairpin structure consisting of two anti-parallel beta...

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Bibliographische Detailangaben
Hauptverfasser: PHILIPPE BULET, PEDRO ISMAEL DA SILVA JUNIO, SIRLEI DAFFRE
Format: Patent
Sprache:por
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Zusammenfassung:The invention refers to small peptides with low hemolytic activity, presenting similar antiparasitic, antifungal and antibacterial activities. More specifically, it refers to a peptide called gomesin, with 18 amino acid residues, configured as a hairpin structure consisting of two anti-parallel beta-folded sheets joined by a beta turn, containing four invariable residues of cysteine forming two disulphide bridges, configurable as a cyclic chain with open or closed ends.