METHOD FOR CYCLOSPORIN PURIFICATION

The invention relates to a method for chromatographic purification of cyclosporin A from a raw product containing cyclosporin complex. A column filled with silicagel is used and multistage chromatography is applied with a column filled with normal phase of silicagel and a mixture of solvents contain...

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Bibliographische Detailangaben
Hauptverfasser: NAGYNE, ARVAI E, DEAK, LAJOS, MAKO, GYOERGYNE, MISKOLCZY, ISTVANNE, KERI, VILMOS
Format: Patent
Sprache:bul ; eng
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Beschreibung
Zusammenfassung:The invention relates to a method for chromatographic purification of cyclosporin A from a raw product containing cyclosporin complex. A column filled with silicagel is used and multistage chromatography is applied with a column filled with normal phase of silicagel and a mixture of solvents containing toluene as a basic component. 13 claims