Dibenzocyclooctaimidazoles - useful as anti inflammatories

Dibenzocyclooctaimidazoles - useful as anti inflammatories

Cpds. of the formula: (where X and Y = H, CH3 CH3O, F, Cl, Br and CH3S; R = CF3, pyridyl, naphthyl, phenyl or phenyl substd. by CH3, CH3O, F Cl, Br, (CH3)2N, CO2H, and CH3S) are claimed together with their acid addn. salts pref. human dose is 3-10 mg/kg/day. Prep. is by reacting corresp. 5,6,11,12-t...

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Bibliographische Detailangaben
1. Verfasser: J.G. LOMBARDINO
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Cpds. of the formula: (where X and Y = H, CH3 CH3O, F, Cl, Br and CH3S; R = CF3, pyridyl, naphthyl, phenyl or phenyl substd. by CH3, CH3O, F Cl, Br, (CH3)2N, CO2H, and CH3S) are claimed together with their acid addn. salts pref. human dose is 3-10 mg/kg/day. Prep. is by reacting corresp. 5,6,11,12-tetrahydrodibenzo/a, e/cyclooctene2-5, 6-dione with RCHO and ammonium acetate.