NOUVEAUX COMPOSES DU TYPE DES PROSTAGLANDINES ET LEUR PROCEDE DE PREPARATION
Prostaglandin analogues of formula (I) E =CH2CH2 or trans- CH=CH-; R1 = H; (1-8C) alkyl or a cation; R2 = (1-5C) alkyl, V = -(CH2)5- or cis-CH=CH- (CH2)3 but is -(CH2)5- when E = -(CH2)2- and W = 1- pentyl (or cis-1-pent-2-enyl when E = trans-CH=CH- and V = -CH-CH-(CH2)3-), have a prolonged and more...
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Zusammenfassung: | Prostaglandin analogues of formula (I) E =CH2CH2 or trans- CH=CH-; R1 = H; (1-8C) alkyl or a cation; R2 = (1-5C) alkyl, V = -(CH2)5- or cis-CH=CH- (CH2)3 but is -(CH2)5- when E = -(CH2)2- and W = 1- pentyl (or cis-1-pent-2-enyl when E = trans-CH=CH- and V = -CH-CH-(CH2)3-), have a prolonged and more specific activity than their natural counterparts. |
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