AROMATIC AZOCYCLICS WITH A BIPHENYL SUBSTITUENT WH
Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis...
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| creator | DANIEL J. KERKMAN ANDREW S. TASKER THOMAS W. VON GELDERN WILLIAM H. HOLLEMAN KAZUMI SHIOSAKI JEFFREY A. KESTER BISWANATH DE THOMAS M. ZYDOWSKY JOHN F. DEBERNARDIS FATIMA Z. BASHA MARTIN WINN SAUL H. ROSENBERG |
| description | Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus. |
| format | Patent |
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TASKER ; THOMAS W. VON GELDERN ; WILLIAM H. HOLLEMAN ; KAZUMI SHIOSAKI ; JEFFREY A. KESTER ; BISWANATH DE ; THOMAS M. ZYDOWSKY ; JOHN F. DEBERNARDIS ; FATIMA Z. BASHA ; MARTIN WINN ; SAUL H. ROSENBERG</creatorcontrib><description>Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus.</description><edition>5</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1992</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920312&DB=EPODOC&CC=AU&NR=8374491A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920312&DB=EPODOC&CC=AU&NR=8374491A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DANIEL J. 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KESTER</creatorcontrib><creatorcontrib>BISWANATH DE</creatorcontrib><creatorcontrib>THOMAS M. ZYDOWSKY</creatorcontrib><creatorcontrib>JOHN F. DEBERNARDIS</creatorcontrib><creatorcontrib>FATIMA Z. BASHA</creatorcontrib><creatorcontrib>MARTIN WINN</creatorcontrib><creatorcontrib>SAUL H. ROSENBERG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DANIEL J. KERKMAN</au><au>ANDREW S. TASKER</au><au>THOMAS W. VON GELDERN</au><au>WILLIAM H. HOLLEMAN</au><au>KAZUMI SHIOSAKI</au><au>JEFFREY A. KESTER</au><au>BISWANATH DE</au><au>THOMAS M. ZYDOWSKY</au><au>JOHN F. DEBERNARDIS</au><au>FATIMA Z. BASHA</au><au>MARTIN WINN</au><au>SAUL H. ROSENBERG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AROMATIC AZOCYCLICS WITH A BIPHENYL SUBSTITUENT WH</title><date>1992-03-12</date><risdate>1992</risdate><abstract>Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AROMATIC AZOCYCLICS WITH A BIPHENYL SUBSTITUENT WH |
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