AROMATIC AZOCYCLICS WITH A BIPHENYL SUBSTITUENT WH

Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DANIEL J. KERKMAN, ANDREW S. TASKER, THOMAS W. VON GELDERN, WILLIAM H. HOLLEMAN, KAZUMI SHIOSAKI, JEFFREY A. KESTER, BISWANATH DE, THOMAS M. ZYDOWSKY, JOHN F. DEBERNARDIS, FATIMA Z. BASHA, MARTIN WINN, SAUL H. ROSENBERG
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Novel pyrimidine, pyridine, pyridazine, pyrazine and triazine compounds are provided of the formula (I). The compounds of the invention are useful for treating hypertension, edema, renal failure, congestive heart failure, psoriasis and glaucoma, and in the prevention and treatment of atherosclerosis or to treat gastrointestinal disorders associated with enhanced contractility and/or motility of intestinal smooth muscle or to treat contractile disorders of the uterus.