Neisserial vaccine compositions and methods

Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria which express genes from virulent strains of Neisseria and/...

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Bibliographische Detailangaben
Hauptverfasser: STEVEN ANTHONY ROCHFORD WEBB, MICHAEL JOHN HUDSON, ANDREW RICHARD GORRINGE, PHILIPPA BRACEGIRDLE, JOHN SIMON KROLL, CLIONA ANNE O'DWYER, KEITH CARTWRIGHT, ANDREW ROBINSON, PAUL RICHARD LANGFORD
Format: Patent
Sprache:eng
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Zusammenfassung:Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria which express genes from virulent strains of Neisseria and/or heterologous gene products from non-neisserial sources. Such compositions are used in vaccine preparations for the treatment of microbial infection.