Amine derivatives as protease inhibitors

The present invention relates to novel alkanoyl-substituted heterocyclic derivatives which are cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.

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Bibliographische Detailangaben
Hauptverfasser:	OLIVER L. SAUNDERS, MICHAEL GRAUPE, DAVID J. ALDOUS, CRAIG J. MOSSMAN, SHEILA ZIPFEL, ROBERT S. MCDOWELL, ARNOLD J. MARTELLI, VALERI MARTICHONOK, FRANK HALLEY, JOHN O. LINK, ANDREAS TIM, SUKANTHINI THURAIRATNAM, STEPHEN D. PICKETT, JOHN W. PATTERSON, MARY E. MCGRATH, JUSTINE LAI, JANA BURGESS-HENRY
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel alkanoyl-substituted heterocyclic derivatives which are cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.