Compositions for treating viral infections, and methods therefor

Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly effective where the subject has resistance to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ALONSO HEREDIA, ROBERT R. REDFIELD, CHARLES E. DAVIS JR
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly effective where the subject has resistance to a nucleoside analogue, where the subject has resting cellular reservoirs of such a virus, or to induce a post-treatment period of replication incompetence of such a virus.