Rac-proteine kinase as therapeutic agent or in diagnostics
The invention concerns RAC-PK protein kinase and fragments thereof, as well as activators and inhibitors of RAC-PK protein kinase for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | The invention concerns RAC-PK protein kinase and fragments thereof, as well as activators and inhibitors of RAC-PK protein kinase for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK protein kinase for use in screening potential mimics or modulators thereof. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. |
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