MOLECULAR SEPARATION COLUMN AND USE THEREOF

A molecular separation column is provided for effecting differential distribution, between two phases, of the components of a sample flowing therethrough, said column containing a solid stationary phase which comprises a porous matrix of fiber having particulate immobilized therein, at least one of...

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Bibliographische Detailangaben
Hauptverfasser: E.A. OSTREICHER, K.C. HOU, A.L. CROWDER, J.V. FIORE, N.L. DAILEY, P.J. MARINACCIO
Format: Patent
Sprache:eng
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Zusammenfassung:A molecular separation column is provided for effecting differential distribution, between two phases, of the components of a sample flowing therethrough, said column containing a solid stationary phase which comprises a porous matrix of fiber having particulate immobilized therein, at least one of said fiber or particulate being effective for molecular separation, preferably the particulate, the matrix being substantially i homogeneous with respect to each component. When used in liquid-solid flow-through molecular separations, there is a reduced pressure drop and diffusional resistance so that the columns can be used for commercial scale liquid separations in addition to analytical separations.A method is also provided for effecting molecular separations by the use of such columns as well as providing for a solid phase for use in such columns.